
CandyFace
Hi and welcome DrageoN

I'll try my best to answer your questions :)
1. Yes, although there is no pressure sensitivity, it works just like your mouse.
2. Yes sorta, PyxelEdit has this great feature where, when you have chosen a colour you like, you can open the colour panel where you are easily able to adjust to good corresponding colours for, for example shading. You also have Lightness/Value, Saturation and Hue, so you have a great opportunity to gather some good looking colours for direct use or for your palette without too much effort.
This is how the colour panel looks like:

I hope that answered your questions
see you aboard soon ;)