Font looks blurry
As you can see the font looks blurry, I've seen that it's a common problem but I can't find a solution, do you have
I think it's because of the resolution of your screen. Maybe try to resize the height of your window. Hope it will work.
This is an issue with the Retina mode.
As a workaround you can run the app from the terminal with this option:
/Applications/PyxelEdit.app/Contents/MacOS/PyxelEdit -AppleMagnifiedMode NO
Hope this help.