whenever i open the program i get no signal to my monitor even though i can click on any other program on my computer
Strange... what kind of monitor are you using?
I'm having the same problem. Been using Pyxel Edit for years without issues, but I recently updated to v.0.4.95, and the no monitor signal began a few days later after a Windows update (unsure if this is what caused the issues, however). I've tried reinstalling and going back to v.0.4.5.. but no luck.